Exipain

Administer orally. Take the tablet whole with a glass of water, preferably with or after food to minimize gastrointestinal discomfort. Do not chew or crush.

Aceclofenac acts primarily by inhibiting prostaglandin synthesis, a process mediated by cyclooxygenase (COX) enzymes. It inhibits both COX-1 and COX-2, leading to reduced production of inflammatory mediators.

• •Hypersensitivity to Aceclofenac, aspirin, or other NSAIDs
• •Active gastrointestinal bleeding or peptic ulcer disease
• •Severe renal or hepatic impairment
• •Severe heart failure
• •Third trimester of pregnancy

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Symptoms of overdose may include headache, nausea, vomiting, epigastric pain, gastrointestinal bleeding, rarely diarrhoea, disorientation, excitation, coma, drowsiness, dizziness, tinnitus, fainting or convulsions. In cases of significant poisoning, acute renal failure and liver damage are possible. Treatment is symptomatic and supportive, including gastric lavage and activated charcoal.

Avoid during the third trimester of pregnancy due to potential effects on fetal cardiovascular system. Use with caution in the first and second trimesters only if clearly needed. Avoid during lactation as NSAIDs can be excreted in breast milk.